Day 1 — Arrive Tunis, evening in Sidi Bou Said
Land at Tunis–Carthage airport. Check in at a hotel in La Marsa, Gammarth or the medina. Evening: dinner in Sidi Bou Said with a sunset coffee at Café des Délices overlooking the bay.
Day 2 — Medina, Bardo, Carthage
Morning in the UNESCO medina of Tunis: Zitouna Mosque, the souks, Tourbet El Bey. Late morning: Bardo Museum (world's largest collection of Roman mosaics — 2h minimum). Afternoon: Carthage by the TGM light rail — Antonine Baths, Byrsa Hill, Roman amphitheatre. Back to Sidi Bou Said for dinner.
Day 3 — Tunis → El Jem → Tozeur
Long driving day (450 km, 5 h). Stop at El Jem to climb inside the world's third-largest Roman amphitheatre. Continue south through the olive groves to Tozeur, arriving by late afternoon. Check in to a desert-edge hotel like the Anantara Sahara Tozeur Resort or The Mora Sahara.
Day 4 — The Sahara
Full day exploring the mountain oases of Chebika and Tamerza, the salt lake Chott el Jerid (Star Wars: A New Hope filming location), and the dunes at Ong Jemel for sunset. Sleep again in Tozeur.
Day 5 — Tozeur → Djerba
Drive south-east to Djerba (340 km, 4 h). Cross by the Roman causeway from El Kantara or take the ferry from Jorf. Check in to a beach hotel on Sidi Mahres.
Day 6–7 — Djerba
Two full beach days with one cultural morning: El Ghriba synagogue, Houmt Souk pottery alleys, sunset at the Borj el Kebir fortress. Fly out from Djerba (DJE) to Europe direct, or back to Tunis to connect.
Alternative — swap the beach for Hammamet
If you prefer easier flight logistics, swap Djerba for Hammamet: drive Tozeur → Hammamet (470 km, 5 h), 3 nights at a Hammamet Bay resort, then 1-hour transfer back to Tunis or Enfidha airport.